seginuscurepharma

Palmisis

Palmisis

Palmitoylethanolamide (PEA)

Palmisis is a pharmaceutical product marketed by Seginus Cure Pharma. It is supplied for professional use and distributed to authorized healthcare channels.

Is an advanced neuro-analgesic formulation designed to support chronic pain management through multi-mechanistic action.

Its micronized Palmitoylethanolamide (PEA) ensures superior absorption and enhanced clinical efficacy in neuropathic, inflammatory, and chronic pain conditions.

PEA is a naturally occurring fatty acid amide that has demonstrated significant effectiveness in reducing diabetic peripheral neuropathic pain. Clinical studies show that PEA treatment reduces pain symptoms within 30 days while also improving inflammation, mood, and sleep quality. This ingredient works by suppressing inflammatory cell activation and limiting pain sensation through neuroprotective and anti-inflammatory properties

Palmisis
tablets-64

L-Carnosine

L-Carnosine is a powerful dipeptide with antioxidant, anti-inflammatory, and neuroprotective properties. Recent clinical research confirms that carnosine supplementation combined with vitamin B complex significantly improves diabetic neuropathy symptoms, including abnormal sensory perception and nerve conduction velocity. It helps protect nerve cells from oxidative damage and reduces inflammation associated with neuropathic pain.
L-Carnosine is a powerful dipeptide with antioxidant, anti-inflammatory, and neuroprotective properties. Recent clinical research confirms that carnosine supplementation combined with vitamin B complex significantly improves diabetic neuropathy symptoms, including abnormal sensory perception and nerve conduction velocity. It helps protect nerve cells from oxidative damage and reduces inflammation associated with neuropathic pain.
tablets-64

L-Arginine

L-Arginine serves as a precursor to nitric oxide (NO) and other metabolites essential for nerve health. Supplementation with L-Arginine has been shown to prevent the development of mechanical hyperalgesia, tactile allodynia, and thermal allodynia in painful diabetic neuropathy. It improves nerve blood flow and conduction velocity, addressing the vascular impairment component of diabetic neuropathy
L-Arginine serves as a precursor to nitric oxide (NO) and other metabolites essential for nerve health. Supplementation with L-Arginine has been shown to prevent the development of mechanical hyperalgesia, tactile allodynia, and thermal allodynia in painful diabetic neuropathy. It improves nerve blood flow and conduction velocity, addressing the vascular impairment component of diabetic neuropathy

Usage / Indications of Palmisis Tablet

It is beneficial in a wide range of pain and nerve conditions:

Neuropathic Pain

Diabetic Peripheral Neuropathy

Sciatica / Radiculopathy

Post-Herpetic Neuralgia

Peripheral Nerve Compression Pain

Musculoskeletal Pain

Chronic Low Back Pain

Myalgia / Fibromyalgia

Osteoarthritis-associated inflammatory pain

Prescription/Dosage Disclaimer

Palmisis is a supplement and is typically used as directed by a healthcare professional. Do not exceed the recommended daily dose.

The information provided is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your physician for any health-related concerns.

Other Conditions

Chronic Pelvic Pain

Post-Surgical Pain

Central Sensitization Disorders

Migraine-associated neuronal inflammation

Highlights

Micronized PEA 300 mg — Superior Bioavailability

Targets Mast Cells & Microglia → Root Cause Pain Relief

Powerful Antioxidant L-Carnosine for Nerve Protection

Enhances Circulation with L-Arginine

Non-NSAID, Non-Opioid, Safe for Long-Term Use

Effective in Neuropathic & Musculoskeletal Pain Spectrum

Key Benefits of Palmisis

✔ Advanced Pain Modulation

PEA reduces neuro-inflammation and nerve hypersensitivity.

✔ Micronized PEA = Faster Relief

Higher absorption → stronger and more consistent analgesic effect.

✔ Triple Action Formula

Anti-inflammatory + anti-oxidant + neuro-protective.

✔ Safe & Well Tolerated

Non-sedating, non-habit forming, GI-friendly.

✔ Supports Nerve Repair

L-carnosine and L-arginine assist in cellular regeneration and microcirculation.

✔ Ideal for Long-Term Pain Management

Can be used safely in chronic pain patients including diabetics and elderly.

Frequently Asked Questions (FAQs)

What is Palmisis used for?

It is used for neuropathic pain, chronic low back pain, sciatica, diabetic neuropathy, fibromyalgia, and inflammatory pain conditions.

How does PEA help in pain?

PEA acts on PPAR-α receptors to reduce mast-cell activation, microglial overactivity, and neuro-inflammation — addressing the root cause of neuropathic pain.

Is it safe for long-term use?

Yes. PEA is an endogenous compound and is well tolerated even during prolonged therapy.

Does it cause drowsiness like other pain medicines?

No. it is non-sedating and does not impair daily activity.

Can diabetic patients take it?

Yes. It is safe for diabetics and beneficial in diabetic neuropathy.

How long does it take to show effect?

Most patients experience relief in 7–14 days, with continued improvement over 4–6 weeks.

Can Palmisis be used along with NSAIDs or neuropathic drugs?

Yes. It can be safely combined with NSAIDs, gabapentinoids, antidepressants, and muscle relaxants.

Are there any common side effects?

Usually none. Mild gastric discomfort may occur in sensitive individuals.

Important Considerations

  • Prescription/Dosage: PALMISIS is a supplement and is typically used as directed by a healthcare professional. Do not exceed the recommended daily dose.
  • Disclaimer: The information provided is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your physician for any health-related concerns.