PRESELIN
Preselin is a pharmaceutical product marketed by Seginus Cure Pharma. It is supplied for professional use and distributed through authorized healthcare channels.
(Pregabalin 75 mg + Methylcobalamin 1500 mcg + Duloxetine Delayed-Release 20 mg)
Smart Triple-Action Therapy for Neuropathic Pain Relief
It is an advanced, synergistic formulation designed to target neuropathic pain at multiple levels—nerve hyperexcitability, neurotransmitter imbalance, and nerve regeneration. With a delayed-release Duloxetine core, it ensures sustained pain modulation with improved tolerability.
Advantages
Triple-mechanism pain control:
Combines central pain modulation, nerve stabilization, and neuro-repair
Delayed-release Duloxetine
for consistent serotonin–norepinephrine reuptake inhibition and reduced GI intolerance
High-strength Methylcobalamin (1500 mcg)
supports nerve regeneration and myelin repair
Once-daily dosing
improves patient compliance in chronic neuropathic conditions
Ideal for moderate to severe neuropathic pain
with associated anxiety or sleep disturbance
Diabetic peripheral neuropathy
Post-herpetic neuralgia
Chronic neuropathic pain (central & peripheral)
Fibromyalgia and neuropathic pain with depressive symptoms
Reduces burning, tingling, and electric-shock–like pain
Improves sleep quality and functional ability
Supports long-term nerve health and recovery
PRESELIN – DLS
(Pregabalin 50 mg + Duloxetine Delayed-Release 10 mg)
Balanced Dual Therapy for Early-Stage Neuropathic Pain
It offers a lower-dose, dual-action approach, making it suitable for early neuropathy, elderly patients, or dose-sensitive individuals requiring effective pain control with improved tolerability.
Advantages
Low-dose dual combination for gentle yet effective neuropathic pain relief
Delayed-release Duloxetine for sustained central pain control
Reduced sedation and dizziness compared to higher-dose regimens
Ideal initiation therapy before step-up to triple combination
Mild to moderate neuropathic pain
Early diabetic neuropathy
Neuropathic pain in elderly or fragile patients
Patients intolerant to high-dose pregabalin
Controls pain with minimal CNS side effects
Improves daily functioning and quality of life
Suitable for long-term management under supervision
Safety Advice
Take the tablet exactly as prescribed by your physician
Avoid alcohol as it may increase dizziness and drowsiness
Use with caution in patients with renal impairment or liver disease
Do not stop medication abruptly; tapering is advised
Disclaimer
This information is intended for educational and informational purposes only and does not substitute professional medical advice. PRESELIN-DM and PRESELIN-DLS should be used only under the guidance of a qualified healthcare professional. Individual responses may vary.
Frequently Asked Questions (FAQs)
It combines pain suppression + mood modulation + nerve repair in one formulation, addressing both symptoms and underlying nerve damage.
it is preferred in early-stage neuropathy, elderly patients, or those requiring lower starting doses.
Most patients experience improvement within 1–2 weeks, with optimal benefit over continued use.
Yes, under medical supervision, they are suitable for chronic neuropathic pain management.
Mild dizziness or sleepiness may occur initially, usually subsiding as the body adjusts.